Possible mechanisms behind cardiac troponin elevations

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چکیده

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Cardiac troponin elevations in patients without acute coronary syndrome.

Cardiac troponin T and troponin I are the most specific and sensitive laboratory markers of myocardial cell injury and therefore have replaced creatine kinase MB as the gold standard.1,2 Accordingly, the new definition of acute myocardial infarctions was based on elevations of cardiac troponins in blood in the setting of ischemia.2 The compelling clinical value of troponins resides in its super...

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Marathon running commonly causes a transient elevation of creatine kinase and cardiac troponin I (cTnI). The use of statins before marathon running exacerbates the release of creatine kinase from skeletal muscle, but the effect of statin use on exercise-induced cTnI release is unknown. We therefore measured cTnI concentrations in statin-using (n = 30) and nonstatin-using (n = 41) runners who pa...

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ژورنال

عنوان ژورنال: Biomarkers

سال: 2018

ISSN: 1354-750X,1366-5804

DOI: 10.1080/1354750x.2018.1490969